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Ep300/CREBBP-IN-4

Ep300/CREBBP-IN-4 (Example 56) is a potent dual inhibitor of EP300 and CREBBP with IC50 values of 24 nM and 64 nM, respectively. It is a valuable chemical probe for oncology research, used to investigate the roles of these acetyltransferases in cancer cell proliferation and tumorigenesis in both cellular and animal models.

Product Specifications

CAS Number

2259641-42-2

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

COc1ccc (cc1) C1 (CC (F) (F) C1) C (=O) N1C[C@H] (F) C[C@@H]1C (=O) Nc1ccc2[nH]ncc2n1

Molecular Formula

C23H22F3N5O3

Molecular Weight

473.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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