PROTAC BCR-ABL1 ligand 1
GMB-475 (PROTAC BCR-ABL1 ligand 1) is a small molecule that induces the degradation of the BCR-ABL1 oncoprotein by recruiting the VHL E3 ligase. This mechanism supports its investigation as a potential therapeutic strategy in chronic myeloid leukemia research, applicable in both cellular and animal models.
Product Specifications
CAS Number
2489876-34-6
Field of Research
Cardiovascular Research, Neuroscience; Cell Biology, Signal Transduction
Smiles
N (C1=CC (C2=CC=C (O) C=C2) =NC=N1) C3=CC=C (OC (F) (F) F) C=C3
Molecular Formula
C17H12F3N3O2
Molecular Weight
347.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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