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PROTAC BCR-ABL1 ligand 1

GMB-475 (PROTAC BCR-ABL1 ligand 1) is a small molecule that induces the degradation of the BCR-ABL1 oncoprotein by recruiting the VHL E3 ligase. This mechanism supports its investigation as a potential therapeutic strategy in chronic myeloid leukemia research, applicable in both cellular and animal models.

Product Specifications

CAS Number

2489876-34-6

Field of Research

Cardiovascular Research, Neuroscience; Cell Biology, Signal Transduction

Smiles

N (C1=CC (C2=CC=C (O) C=C2) =NC=N1) C3=CC=C (OC (F) (F) F) C=C3

Molecular Formula

C17H12F3N3O2

Molecular Weight

347.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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