INY-03-041 trihydrochloride

INY-03-041 trihydrochloride is a potent, selective PROTAC pan-AKT degrader, constructed from Ipatasertib and Lenalidomide. It potently degrades AKT1, AKT2, and AKT3 (IC50 = 2.0, 6.8, and 3.5 nM) and serves as a valuable chemical tool for probing AKT signaling in cancer research, both in vitro and in vivo.