AUTAC1
AUTAC1 is a MetAP2-targeted AUTAC degrader that induces the autophagic clearance of MetAP2 and FKBP12. This small molecule probe is useful for studying targeted protein degradation, autophagy pathways, and PROTAC development in both cellular and animal models of cancer research.
Product Specifications
CAS Number
2241669-09-8
Product Name Alternative
AUTACs
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
99.45% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.54 mM) ; DMSO:80 mg/mL (85.92 mM)
Smiles
C[C@@]1 ([C@@]2 ([C@@]3 (CO3) CC[C@@H] (OC (NCCCOCCOCCOCCCNC ([C@H] (CSC=4N (CC5=CC=C (F) C=C5) C6=C (N4) C (=O) N=C (N) N6) NC (C) =O) =O) =O) [C@H]2OC) [H]) [C@H] (CC=C (C) C) O1
Molecular Formula
C44H63FN8O11S
Molecular Weight
931.08
Storage Conditions
-20°C
Notes
For research use only.
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