Bicuculline methochloride
Bicuculline methochloride is a competitive GABAA receptor antagonist and allosteric inhibitor with an IC50 of 1.7 μM. It is widely used in neuroscience research to study epilepsy, synaptic transmission, and inhibitory neural circuits, employing both in vitro electrophysiology and in vivo seizure models.
Product Specifications
CAS Number
38641-83-7
Product Name Alternative
(-) -Bicuculline methochloride
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.35% (May vary between batches)
Solubility
H2O:40 mg/mL (95.73 mM)
Smiles
C[N+]1 (C) [C@] ([C@]2 (C3=C (C (=O) O2) C4=C (C=C3) OCO4) [H]) (C5=C (C=C6C (=C5) OCO6) CC1) [H].[Cl-]
Molecular Formula
C21H20ClNO6
Molecular Weight
417.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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