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PROTAC Bcl-xL degrader-2

PROTAC Bcl-xL degrader-2 is a potent, VHL-based small molecule that selectively degrades the anti-apoptotic protein Bcl-xL with an IC50 of 0.6 nM. This tool compound is valuable for probing Bcl-xL biology in cancer research and has demonstrated utility in both cellular and in vivo models for studying apoptosis and therapeutic resistance.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Molecular Formula

C68H80N8O14S3

Molecular Weight

1329.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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