Larsucosterol trimethylamine
Larsucosterol trimethylamine (DUR-928) is a liver X receptor (LXR) antagonist with epigenetic modulatory activity. It reduces hepatic lipid accumulation, suppresses LPS- and TNFα-driven inflammation in macrophages, and demonstrates protective effects in models of LPS- and acetaminophen-induced organ injury.
Product Specifications
Product Name Alternative
DV-928 trimethylamine, DUR-928 trimethylamine, LXR, Liver X Receptor, LiverXReceptor
Field of Research
Metabolism Research
Purity
97.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (3.69 mM) ; DMSO:20 mg/mL (36.91 mM)
Smiles
C[C@@H] ([C@H]1CC[C@@H]2[C@]1 (C) CC[C@H]3[C@H]2CC=C4[C@]3 (C) CC[C@H] (OS (=O) (O) =O) C4) CCCC (C) (O) C.CN (C) C
Molecular Formula
C30H55NO5S
Molecular Weight
541.83
Storage Conditions
-20°C
Notes
For research use only.
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