LEB-03-144
LEB-03-144 is a deubiquitinase-targeting chimera (DUBTAC) designed to stabilize the WEE1 kinase by recruiting OTUB1 to it, utilizing AZD1775 linked to EN523. It has demonstrated WEE1 protein stabilization in cellular models like HEP3B hepatoma cells, providing a tool for investigating targeted protein stabilization in cancer research.
Product Specifications
Molecular Formula
C43H51N11O6
Molecular Weight
817.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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