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LEB-03-153

LEB-03-153 is a deubiquitinase-targeting chimera (DUBTAC) that recruits OTUB1 to the WEE1 kinase inhibitor AZD1775 (Adavosertib) via a linker-free connection. This bifunctional molecule is a research tool for investigating targeted protein stabilization and has been utilized in cellular studies to explore WEE1's role in DNA damage response and cell cycle regulation.

Product Specifications

Molecular Formula

C40H44N10O6

Molecular Weight

760.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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