GSK-3β inhibitor 12
GSK-3β inhibitor 12 (compound 15) is an inhibitor of GSK-3β. GSK-3β inhibitor 12 inhibits 49.11% and 37.11% activity of 25 μM and 50 μM GSK-3β, respectively. GSK-3β inhibitor 12 can be used for the research of neurodegenerative diseases[1].
Product Specifications
CAS Number
784170-07-6
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk-3β-inhibitor-12.html
Purity
99.81
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(CC1=CNC2=C1C=CC=C2)NC3=NC=C(C)S3
Molecular Formula
C14H13N3OS
Molecular Weight
271.34
Precautions
H315, H319, H320
References & Citations
[1]Martinez Gil A, et al. N- (2-Thiazolyl) -amide derivatives as GSK-3 inhibitors. EP20060380099. 2007
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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