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FAK PROTAC B5

Compound B5 (FAK PROTAC B5) is a potent and selective FAK degrader with an IC50 of 14.9 nM, demonstrating excellent antiproliferative activity and inhibition of cell migration and invasion in vitro. Its favorable plasma stability and permeability support its utility in cancer research, particularly for studying metastasis and tumor progression in cellular models.

Product Specifications

CAS Number

2471525-44-5

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Smiles

CNC (=O) c1ccccc1Nc1nc (Nc2ccc (cc2OC) N2CCN (CCCCC (=O) Nc3cccc4C (=O) N (C5CCC (=O) NC5=O) C (=O) c34) CC2) ncc1Cl

Molecular Formula

C41H43ClN10O7

Molecular Weight

823.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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