FAK PROTAC B5
Compound B5 (FAK PROTAC B5) is a potent and selective FAK degrader with an IC50 of 14.9 nM, demonstrating excellent antiproliferative activity and inhibition of cell migration and invasion in vitro. Its favorable plasma stability and permeability support its utility in cancer research, particularly for studying metastasis and tumor progression in cellular models.
Product Specifications
CAS Number
2471525-44-5
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CNC (=O) c1ccccc1Nc1nc (Nc2ccc (cc2OC) N2CCN (CCCCC (=O) Nc3cccc4C (=O) N (C5CCC (=O) NC5=O) C (=O) c34) CC2) ncc1Cl
Molecular Formula
C41H43ClN10O7
Molecular Weight
823.3
Storage Conditions
-20°C
Notes
For research use only.
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