PROTAC EGFR degrader 3
PROTAC EGFR Degrader 3 is a potent and selective compound that effectively degrades mutant EGFR in cellular models such as H1975 and HCC827 cells. Its mechanism involves lysosomal pathways, making it a valuable chemical probe for studying targeted protein degradation in oncology research, both in vitro and in vivo.
Product Specifications
CAS Number
2768472-28-0
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C[C@H] (NC (=O) [C@@H]1C[C@@H] (O) CN1C (=O) [C@@H] (NC (=O) CCCCCCCN1CCN (CC1) c1ccc (Nc2ncc3nc (Nc4ccccc4) n ([C@H]4CCCN (C4) C (=O) C=C) c3n2) cc1) C (C) (C) C) c1ccc (cc1) -c1scnc1C
Molecular Formula
C60H77N13O5S
Molecular Weight
1092.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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