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PP-C8

PP-C8 is a potent and selective PROTAC that degrades CDK12 and Cyclin K with DC50 values of approximately 410 nM. It demonstrates synergistic antiproliferative activity with PARP inhibitors in triple-negative breast cancer models, making it a valuable chemical probe for oncology research targeting transcription-associated kinases.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Molecular Formula

C43H51FN12O7

Molecular Weight

866.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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