PP-C8
PP-C8 is a potent and selective PROTAC that degrades CDK12 and Cyclin K with DC50 values of approximately 410 nM. It demonstrates synergistic antiproliferative activity with PARP inhibitors in triple-negative breast cancer models, making it a valuable chemical probe for oncology research targeting transcription-associated kinases.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Molecular Formula
C43H51FN12O7
Molecular Weight
866.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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