MEK/PI3K-IN-1
MEK/PI3K-IN-1 (6r) is a dual MEK and PI3K inhibitor with IC50 values of 124 nM for MEK1 and 130/236 nM for PI3Kα/δ. It suppresses pERK and pAKT signaling, demonstrating anti-proliferative activity in cancer cell lines, which supports its use in oncology research for studying pathway crosstalk.
Product Specifications
CAS Number
2281803-28-7
Field of Research
Signal Transduction
Smiles
FC (F) c1nc2ccccc2n1-c1nc (NCCOCCOCCOCCONC (=O) c2ccc (F) c (F) c2Nc2ccc (I) cc2F) nc (n1) N1CCOCC1
Molecular Formula
C36H37F5IN9O6
Molecular Weight
913.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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