What is the catalog number for LEB-03-146?

The catalog number for LEB-03-146 is orb1983002.

What sizes are available for LEB-03-146?

LEB-03-146 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does LEB-03-146 come in?

LEB-03-146 is available in 2 different pack sizes.

Is LEB-03-146 in stock?

LEB-03-146 is currently made to order / not held in immediate stock. Contact us for lead time.

LEB-03-146

LEB-03-146 is a deubiquitinase-targeting chimera (DUBTAC) that stabilizes the WEE1 kinase by recruiting OTUB1 to it via a proteolysis-targeting chimera strategy. It has demonstrated effective WEE1 protein stabilization in cellular studies, such as in HEP3B hepatoma cells, providing a novel chemical tool for oncology and targeted protein stabilization research.

Product Specifications

CAS Number

2858812-91-4

Field of Research

Cell Biology

Smiles

CC (C) (O) c1cccc (n1) -n1n (CC=C) c (=O) c2cnc (Nc3ccc (cc3) N3CCN (CCOCCOCCNC (=O) CCc4ccc (o4) N4CCN (CC4=O) C (=O) C=C) CC3) nc12

Molecular Formula

C46H57N11O8

Molecular Weight

892.01

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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