PROTAC ERα Y537S degrader-1
PROTAC ERα Y537S degrader-1 is a heterobifunctional molecule designed to target the estrogen receptor alpha Y537S mutant for degradation. It consists of an ERα-binding ligand, an E3 ligase recruiter, and a connecting linker. This compound is a research tool for studying mutant ERα biology and targeted protein degradation in breast cancer models, both in cellular and animal studies.
Product Specifications
CAS Number
2667598-05-0
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
Oc1ccc2[C@H] ([C@H] (CCc2c1) c1ccccc1) c1ccc (cc1) N1CCC (CN2CCN (CC2) c2cc3CN (C4CCC (=O) NC4=O) C (=O) c3c3OCOc23) CC1
Molecular Formula
C46H49N5O6
Molecular Weight
767.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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