XY-06-007
XY-06-007 is a potent and selective bump-and-hole PROTAC designed to degrade the BRD4 BD1 L94V mutant with a DC50 of 10 nM at 6 hours, showing minimal off-target activity. Its favorable pharmacokinetic profile supports its use for probing BET bromodomain function in both cellular and animal models of cancer and transcriptional regulation.
Product Specifications
CAS Number
2757045-94-4
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
[H][C@]1 (N=C (c2ccc (Cl) cc2) c2cc (OC) ccc2-n2c (C) nnc12) [C@@H] (C) C (=O) NCCCCCNC (=O) COc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12
Molecular Formula
C41H41ClN8O8
Molecular Weight
809.27
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
