Tri (TLR4-IN-C34-PEG2-amide-PEG1) -amide-C3-COOH

This chemical linker incorporates the TLR4 inhibitor TLR4-IN-C34, which attenuates TLR4 signaling in enterocytes and macrophages. It has been shown to reduce systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis, supporting its use in related in vivo and in vitro inflammation research.