Tri (TLR4-IN-C34-C2-amide-C3-amide-PEG1) -amide-C3-COOH
This small molecule linker incorporates the TLR4 inhibitor TLR4-IN-C34. It effectively suppresses TLR4 signaling in both enterocytes and macrophages, demonstrating efficacy in reducing systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis, making it a valuable research tool for studying innate immunity and inflammatory pathways.
Product Specifications
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Cell Biology, Pharmacology & Drug Discovery
Molecular Formula
C84H134N10O39
Molecular Weight
1908.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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