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Tri (TLR4-IN-C34-C2-amide-C3-amide-PEG1) -amide-C3-COOH

This small molecule linker incorporates the TLR4 inhibitor TLR4-IN-C34. It effectively suppresses TLR4 signaling in both enterocytes and macrophages, demonstrating efficacy in reducing systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis, making it a valuable research tool for studying innate immunity and inflammatory pathways.

Product Specifications

Field of Research

Immunology & Inflammation, Immunology & Inflammation; Cell Biology, Pharmacology & Drug Discovery

Molecular Formula

C84H134N10O39

Molecular Weight

1908.01

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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