Antitumor agent-36

Antitumor agent-36 is a potent small molecule that inhibits cancer cell proliferation and metastasis by inducing DNA damage (γ-H2AX/p53) and mitochondrial apoptosis (Bcl-2/Bax/caspase-3) . It also acts as a PD-L1 inhibitor, enhancing antitumor immunity via increased CD3+/CD8+ T-cell infiltration in tumor models, supporting its study in oncology and immunotherapy research.