SHP2 protein degrader-2
SHP2-D26 is a PROTAC-based degrader that potently reduces SHP2 protein levels in diverse cancer cell lines. This tool compound is valuable for investigating SHP2-dependent signaling pathways in oncology research, supporting both in vitro cellular studies and in vivo preclinical models.
Product Specifications
CAS Number
2740582-16-3
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C[C@@H] (NC (=O) [C@H]1C[C@H] (O) CN1C (=O) [C@H] (NC (=O) CCCCCCCCN1CCN (CC1) C (=O) CCC (=O) Nc1cccc (Sc2ncc (nc2N) N2CCC (C) (N) CC2) c1Cl) C (C) (C) C) c1ccc (cc1) -c1scnc1C
Molecular Formula
C56H79ClN12O6S2
Molecular Weight
1115.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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