JPS035
JPS035 is a VHL-based PROTAC that selectively degrades HDAC1/2. Its potent degradation activity modulates gene expression and induces apoptosis in cellular models like HCT116, supporting its use in oncology and epigenetics research.
Product Specifications
CAS Number
2669785-84-4
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
CC (=O) N[C@H] (C (=O) N1C[C@H] (O) C[C@H]1C (=O) NCc1ccc (cc1OCCCCCCCCCCCC (=O) Nc1ccc (cc1) C (=O) Nc1ccccc1N) -c1scnc1C) C (C) (C) C
Molecular Formula
C49H65N7O7S
Molecular Weight
896.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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