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JPS035

JPS035 is a VHL-based PROTAC that selectively degrades HDAC1/2. Its potent degradation activity modulates gene expression and induces apoptosis in cellular models like HCT116, supporting its use in oncology and epigenetics research.

Product Specifications

CAS Number

2669785-84-4

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Smiles

CC (=O) N[C@H] (C (=O) N1C[C@H] (O) C[C@H]1C (=O) NCc1ccc (cc1OCCCCCCCCCCCC (=O) Nc1ccc (cc1) C (=O) Nc1ccccc1N) -c1scnc1C) C (C) (C) C

Molecular Formula

C49H65N7O7S

Molecular Weight

896.15

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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