Clenbuterol (hydrochloride)

Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage[1][2][3].

Product Specifications

CAS Number

[21898-19-1]

Product Name Alternative

NAB-365 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H301

Target

Adrenergic Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Clenbuterol_hydrochloride.html

Purity

99.98

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

OC(CNC(C)(C)C)C1=CC(Cl)=C(N)C(Cl)=C1.[H]Cl

Molecular Formula

C12H19Cl3N2O

Molecular Weight

313.65

Precautions

H301

References & Citations

[1]O'Donnell JM, et al. Effects of clenbuterol and antidepressant drugs on beta adrenergic receptor/N-protein coupling in the cerebral cortex of the rat.J PharmacolExpTher. 1985 Jul;234 (1) :30-6.|[2]Culmsee C, Stumm RK, Schäfer MK, Weihe E, Krieglstein J. Clenbuterol induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage. Eur J Pharmacol. 1999;379 (1) :33-45. |[3]Kim J, t al. The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility. Proc Natl Acad Sci U S A. 2020;117 (22) :12435-12443.