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NHEJ inhibitor-1

NHEJ Inhibitor-1 (Compound C2) is a trifunctional platinum complex that overcomes cisplatin resistance in NSCLC by inhibiting Ku70 and Rad51-mediated DNA repair pathways. It further induces ROS production and reduces mitochondrial membrane potential, demonstrating efficacy in both cellular and animal models of lung cancer.

Product Specifications

Field of Research

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C30H35N7O8PtS

Molecular Weight

848.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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