NHEJ inhibitor-1
NHEJ Inhibitor-1 (Compound C2) is a trifunctional platinum complex that overcomes cisplatin resistance in NSCLC by inhibiting Ku70 and Rad51-mediated DNA repair pathways. It further induces ROS production and reduces mitochondrial membrane potential, demonstrating efficacy in both cellular and animal models of lung cancer.
Product Specifications
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C30H35N7O8PtS
Molecular Weight
848.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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