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HD-TAC7

HD-TAC7 is a potent PROTAC-based degrader of HDAC1, HDAC2, and HDAC3, with respective IC50 values of 3.6 μM, 4.2 μM, and 1.1 μM. It reduces NF-κB p65 levels in RAW 264.7 macrophages and is a research tool for studying inflammatory diseases like asthma and COPD.

Product Specifications

CAS Number

2978763-95-8

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.70% (May vary between batches)

Smiles

O=C (NC1=CC=C (F) C=C1N) C2=CC=C (C=C2) NC (=O) CCCCNC (=O) CNC3=CC=CC=4C (=O) N (C (=O) C34) C5C (=O) NC (=O) CC5

Molecular Formula

C33H32FN7O7

Molecular Weight

657.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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