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Rofapitide tetraxetan

Rofapitide tetraxetan (FAP-2286) is a potent and selective fibroblast activation protein (FAP) inhibitor with low nanomolar affinity. This DOTA-conjugated compound enables targeted imaging of the tumor stroma, as demonstrated by its use in preclinical and clinical PET imaging studies when radiolabeled with isotopes like 68Ga.

Product Specifications

CAS Number

2581741-18-4

Field of Research

Immunology & Inflammation

Purity

95.46% (May vary between batches)

Solubility

DMSO:≥ 40 mg/mL; H2O:≥ 80 mg/mL

Smiles

[H][C@@]12CCCN1C (=O) [C@]1 ([H]) CCCN1C (=O) [C@H] (CSCc1cc (CSCCNC (=O) CN3CCN (CC (O) =O) CCN (CC (O) =O) CCN (CC (O) =O) CC3) cc (CSC[C@H] (NC (=O) [C@H] (Cc3ccccc3) NC (=O) [C@H] (CCC (N) =O) NC (=O) [C@@] ([H]) (NC2=O) [C@@H] (C) O) C (O) =O) c1) NC (=O) CCCCC

Molecular Formula

C67H99N13O18S3

Molecular Weight

1470.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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