Rofapitide tetraxetan
Rofapitide tetraxetan (FAP-2286) is a potent and selective fibroblast activation protein (FAP) inhibitor with low nanomolar affinity. This DOTA-conjugated compound enables targeted imaging of the tumor stroma, as demonstrated by its use in preclinical and clinical PET imaging studies when radiolabeled with isotopes like 68Ga.
Product Specifications
CAS Number
2581741-18-4
Field of Research
Immunology & Inflammation
Purity
95.46% (May vary between batches)
Solubility
DMSO:≥ 40 mg/mL; H2O:≥ 80 mg/mL
Smiles
[H][C@@]12CCCN1C (=O) [C@]1 ([H]) CCCN1C (=O) [C@H] (CSCc1cc (CSCCNC (=O) CN3CCN (CC (O) =O) CCN (CC (O) =O) CCN (CC (O) =O) CC3) cc (CSC[C@H] (NC (=O) [C@H] (Cc3ccccc3) NC (=O) [C@H] (CCC (N) =O) NC (=O) [C@@] ([H]) (NC2=O) [C@@H] (C) O) C (O) =O) c1) NC (=O) CCCCC
Molecular Formula
C67H99N13O18S3
Molecular Weight
1470.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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