DTAG-47
DTAG-47 is a heterobifunctional degrader that selectively targets the mutant FKBP12 (F36V) domain, enabling the rapid elimination of dTAG-fused proteins of interest. It is a valuable chemical tool for studying protein function in models of basal-like breast cancer and other malignancies, with utility in both cellular and in vivo research.
Product Specifications
CAS Number
2265886-81-3
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
CC[C@H] (C (=O) N1CCCC[C@H]1C (=O) O[C@H] (CCc1ccc (OC) c (OC) c1) c1ccccc1OCC (=O) NCCCCCCCCNc1ccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c2c1) c1cc (OC) c (OC) c (OC) c1
Molecular Formula
C59H73N5O14
Molecular Weight
1076.24
Storage Conditions
-20°C
Notes
For research use only.
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