M4K2234
M4K2234 is a potent and selective ALK2 inhibitor (IC50 = 5 nM) with >400-fold selectivity over ALK5. This chemical probe is a valuable tool for investigating BMP signaling mechanisms and studying diseases like fibrodysplasia ossificans progressiva (FOP) and certain cancers in both cellular and animal models.
Product Specifications
CAS Number
2421141-51-5
Product Name Alternative
M4K-2234, M4K 2234
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.99% (May vary between batches)
Solubility
DMSO:80 mg/mL (172.95 mM)
Smiles
O=C (N) C1=C (F) C=C (C=C1OC) C2=CN=CC (C3=CC=C (C=C3) N4CCN (CC4) C (C) C) =C2C
Molecular Formula
C27H31FN4O2
Molecular Weight
462.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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