Setidegrasib
Setidegrasib is a PROTAC degrader that selectively targets KRAS G12D mutant protein for proteasomal degradation. This quinazoline-linked prolinamide compound is a valuable research tool for investigating KRAS-driven cancers in both cellular and animal models.
Product Specifications
CAS Number
2821793-99-9
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.49% (May vary between batches)
Smiles
O (CC1=CC=C (C=C1) C2=CN ([C@H] (C (=O) N3[C@H] (C (N[C@@H] (CO) C4=CC=C (C=C4) C5=C (C) N=CS5) =O) C[C@@H] (O) C3) [C@H] (C) C) N=N2) C6=C (C (=CC7=C6N=C (OC8CCOCC8) N=C7N9[C@]%10 (C[C@@] (C9) (NC%10) [H]) [H]) C%11CC%11) C%12=C%13C (=CC (F) =C%12C) NN=C%13
Molecular Formula
C60H65FN12O7S
Molecular Weight
1117.30
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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