KTX-955
KTX-955 is a potent and selective IRAK4 degrader with a DC50 of 5 nM for IRAK4 and 130 nM for Ikaros. This small molecule is a valuable research tool in oncology, supporting both in vitro and in vivo studies to investigate IRAK4's role in cancer signaling pathways.
Product Specifications
CAS Number
2573302-50-6
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CC (C) (O) c1cc2nn (cc2cc1NC (=O) c1cccc (n1) C (F) (F) F) [C@H]1CC[C@H] (CN2CCC (CC2) O[C@H]2C[C@@H] (C2) Nc2cccc3C (=O) N (C4CCC (=O) NC4=O) C (=O) c23) CC1
Molecular Formula
C46H51F3N8O7
Molecular Weight
884.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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