KTX-497
KTX-497 is a potent and selective IRAK4 degrader with a DC50 of 3 nM. This small molecule is a valuable research tool for oncology, enabling the study of IRAK4's role in cancer cell signaling and tumor progression in both in vitro and in vivo models.
Product Specifications
CAS Number
2432993-46-7
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CC (C) (O) c1cc2nn (cc2cc1NC (=O) c1cccc (n1) C (F) (F) F) [C@H]1CC[C@H] (CN2CCC3 (CC (C3) Nc3cccc4C (=O) N (C5CCC (=O) NC5=O) C (=O) c34) CC2) CC1
Molecular Formula
C45H49F3N8O6
Molecular Weight
854.92
Storage Conditions
-20°C
Notes
For research use only.
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