KTX-951
KTX-951 is a potent IRAK4-targeting PROTAC degrader with a DC50 of 18 nM. It shows 22% oral bioavailability in rats at 10 mg/kg and exhibits promising anticancer activity in research models, supporting its investigation in oncology and inflammation-related studies.
Product Specifications
CAS Number
2573298-36-7
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
COc1cc2nn (cc2cc1NC (=O) c1cccc (n1) C (C) (F) F) [C@H]1CC[C@H] (CN2CCC3 (CC (CCNc4cccc5C (=O) N (C6CCC (=O) NC6=O) C (=O) c45) C3) CC2) CC1
Molecular Formula
C46H52F2N8O6
Molecular Weight
850.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV643330 1.0 µg DNA
RGD1309079 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
Sign In for Pricing
View Details