NecroIr1
NecroIr1 is an iridium (III) complex that induces necroptosis in cisplatin-resistant A549R lung cancer cells by selectively targeting mitochondria. It triggers oxidative stress, reduces MMP, and activates the RIPK3/MLKL pathway while modulating CDK4, offering a research tool for overcoming chemotherapy resistance in vitro.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Molecular Formula
C40H29ClIrN5O-
Molecular Weight
823.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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