Daraxonrasib
Daraxonrasib (RMC-6236) is a novel, orally bioavailable inhibitor that targets multiple RAS variants in their active GTP-bound state. This investigational compound demonstrates anti-tumor activity in preclinical models, supporting its use in research on RAS-driven cancers, including in vitro cellular assays and in vivo xenograft studies.
Product Specifications
CAS Number
2765081-21-6
Product Name Alternative
RAS-IN-2, Ras, RMC6236, RMC-6236, RMC-6236
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.24% (May vary between batches)
Solubility
DMSO:200 mg/mL (246.59 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (6.16 mM)
Smiles
CN1CCN (C2=C[C@] ([C@]3=C (CC (C) (C) COC ([C@H]4NN (C ([C@@H] (NC ([C@H]5C[C@@H]5C) =O) CC6=NC7=CS6) =O) CCC4) =O) C8=C (C=CC7=C8) N3CC) =C ([C@H] (C) OC) N=C2) CC1
Molecular Formula
C44H58N8O5S
Molecular Weight
811.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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