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Daraxonrasib

Daraxonrasib (RMC-6236) is a novel, orally bioavailable inhibitor that targets multiple RAS variants in their active GTP-bound state. This investigational compound demonstrates anti-tumor activity in preclinical models, supporting its use in research on RAS-driven cancers, including in vitro cellular assays and in vivo xenograft studies.

Product Specifications

CAS Number

2765081-21-6

Product Name Alternative

RAS-IN-2, Ras, RMC6236, RMC-6236, RMC-6236

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.24% (May vary between batches)

Solubility

DMSO:200 mg/mL (246.59 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (6.16 mM)

Smiles

CN1CCN (C2=C[C@] ([C@]3=C (CC (C) (C) COC ([C@H]4NN (C ([C@@H] (NC ([C@H]5C[C@@H]5C) =O) CC6=NC7=CS6) =O) CCC4) =O) C8=C (C=CC7=C8) N3CC) =C ([C@H] (C) OC) N=C2) CC1

Molecular Formula

C44H58N8O5S

Molecular Weight

811.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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