PROTAC FLT3/CDK9 degrader-1

PROTAC FLT3/CDK9 degrader-1 is a potent, bifunctional small molecule that simultaneously induces the degradation of FLT3 and CDK9 proteins. It effectively triggers apoptosis in cellular models and shows research potential for acute myeloid leukemia (AML), particularly those harboring FLT3-ITD mutations, as supported by published in vitro studies.