LAS190792
LAS190792 (AZD8999) is a dual-acting muscarinic antagonist and β2-adrenoceptor agonist with high receptor potency, particularly at M4 (pIC50 9.2) and β2 (pIC50 9.1) . This pharmacological profile supports its investigation as a bronchodilator in respiratory disease research, including in vitro binding assays and in vivo models of airway constriction.
Product Specifications
CAS Number
1347232-69-2
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
COc1cc (NC (=O) OCCN (C) [C@H]2CC[C@@H] (CC2) OC (=O) C (O) (c2cccs2) c2cccs2) c (Cl) cc1CNC[C@H] (O) c1ccc (O) c2[nH]c (=O) ccc12
Molecular Formula
C39H43ClN4O9S2
Molecular Weight
811.36
Storage Conditions
-20°C
Notes
For research use only.
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