12-Hydroxynevirapine
12-Hydroxynevirapine is a key oxidative metabolite of the antiviral drug Nevirapine. It is bioactivated by sulphotransferases (SULTs) to form the reactive 12-sulphoxy-nevirapine, a process studied to understand Nevirapine's idiosyncratic hepatotoxicity and skin rash adverse effects in both in vitro and in vivo research models.
Product Specifications
CAS Number
133627-24-4
Field of Research
Metabolism Research
Smiles
OCc1ccnc2N (C3CC3) c3ncccc3C (=O) Nc12
Molecular Formula
C15H14N4O2
Molecular Weight
282.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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