18β-Glycyrrhetyl-3-O-sulfate
18β-Glycyrrhetyl-3-O-sulfate is a major metabolite of glycyrrhetinic acid and a potent inhibitor of 11β-HSD2 (IC50 = 0.10 μM) . It is a substrate for OAT1 and OAT3 transporters and is used in research on pseudohyperaldosteronism and anti-inflammatory mechanisms in both in vitro and in vivo models.
Product Specifications
CAS Number
10251-38-4
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
[H][C@@]12C[C@] (C) (CC[C@]1 (C) CC[C@]1 (C) C2=CC (=O) [C@]2 ([H]) [C@@]3 (C) CC[C@H] (OS (O) (=O) =O) C (C) (C) [C@]3 ([H]) CC[C@@]12C) C (O) =O
Molecular Formula
C30H46O7S
Molecular Weight
550.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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