MTX-23
MTX-23 is a PROTAC degrader targeting the androgen receptor (AR), effectively eliminating both full-length (AR-FL) and splice variant (AR-V7) proteins. It demonstrates potent anti-proliferative and pro-apoptotic activity in prostate cancer cell models, making it a valuable tool for investigating AR-dependent signaling and resistance mechanisms in vitro.
Product Specifications
CAS Number
2488296-74-6
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C (NCCCCC (=O) N[C@@H] (C (C) (C) C) C (=O) N1[C@@H] (C[C@@H] (O) C1) C (=O) N[C@@H] (C) C2=CC=C (C=C2) C3=C (C) N=CS3) COC4=C (C=CC (F) =C4F) C5N=C (SC=5) N6CCOCC6
Molecular Formula
C43H53F2N7O7S2
Molecular Weight
882.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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