TUS-007
TUS-007 is an orally bioavailable CANDDY-based degrader that potently and selectively targets KRAS G12D/V mutants for degradation. It demonstrates effective chemical knockdown in vitro and has shown promising tumor growth suppression in vivo, making it a valuable tool for oncology and targeted protein degradation research.
Product Specifications
CAS Number
2227029-18-5
Field of Research
Signal Transduction
Smiles
CC[C@@H] (C) [C@H] (NC (=O) CCCCCCNC (=O) [C@H] (CC (C) C) NC (=O) CNC (=O) c1cc (Cl) ccc1Cl) C (=O) Nc1ccc2nc (Cc3c[nH]c4ccccc34) [nH]c2c1
Molecular Formula
C44H54Cl2N8O5
Molecular Weight
845.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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