JNJ-28583113
JNJ-28583113 is a brain-penetrant TRPM2 antagonist that promotes GSK3α/β phosphorylation, conferring protection against oxidative stress-induced cell death. It suppresses pro-inflammatory microglial activation, making it a valuable tool for in vitro and in vivo research in neurodegenerative and neuroinflammatory disease models.
Product Specifications
CAS Number
2765255-93-2
Product Name Alternative
JNJ28583113
Field of Research
Pharmacology & Drug Discovery
Purity
98.57% (May vary between batches)
Solubility
DMSO:80 mg/mL (218.35 mM)
Smiles
O=C (OCC) CN1N=C (C=2C=CC (=CC2) C (F) (F) F) C3=C1CCCCC3
Molecular Formula
C19H21F3N2O2
Molecular Weight
366.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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