UT-11
UT-11 is a brain-penetrant small molecule inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1) . It demonstrates potent inhibition of PGE2 synthesis with IC50 values of 0.10 μM in human SK-N-AS cells and 2.00 μM in murine BV2 cells. This inhibitor is a valuable research tool for studying neuroinflammation and pain pathways in both cellular and animal models.
Product Specifications
Field of Research
Immunology & Inflammation
Molecular Formula
C17H19Cl2N3O2S
Molecular Weight
400.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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